Donald L. Katz Collegiate Professor of Chemical Engineering
3408 G.G. Brown
FAX: (734) 764-7453
Microfluidic MEMS devices DNA, peptide synthesis and genetic diagnostics, micro reactors for fuel processors, environmental catalysis.
Gulari Research Group Page
|B.S.||Robert's College||Chemical Engineering||1969|
|University of Michigan
Chemical Engineering Department
Ann Arbor, Michigan
Donald L. Katz Collegiate Chair, Professor, 2003 - present
University of Michigan
|Komili Inc. , Ayvalik, Turkey
Technical Manager, 1974 - 1976
Honors and Awards
|Department of Chemical Engineering Outstanding Achievement Award, 2002|
|College of Engineering, Excellence in Service Award, 1995.
|Department of Chemical Engineering, Departmental Research Excellence Award, 1994.
|Chemical Engineer of the Year Award, AIChE Detroit Chapter, 1990.
|ASEE AT&T Foundation Award (for Excellence as an Engineering Educator) of the American Society of Engineering Educators, 1989.
|Faculty Recognition Award for 1985-1986, Highest Award given by the University of Michigan to its Faculty .
|Excellence in Research Award , Engineering College , University of Michigan , 1984 .
|Featured as the Chemical Engineering Educator , J. Chemical Engineering Education, Summer 1984 issue.
|Outstanding Teacher and Leadership Award , Phi Lambda Upsilon Delta Chapter, April, 1981.
|Albert Long Hall Award , given to the graduating class valedictorian, Robert's College, 1969.
|Fulbright Scholar, 1969 - 1974 .
|Earle C. Anthony Fellow , California Institute of Technology, 1970-1971.|
|NIH SBIR study section,
||2002 - present|
|NIH software study section, 2004 - present
||2004 - present|
My group’s research is on reactions at interfaces and developing microfluidic MEMS devices for biosynthesis and genetic diagnosis.
Currently the largest effort in my group is devoted towards making “biochips” or DNA and peptide chips for gene expression, SNP detection and drug – protein interactions. We are into our third generation DNA chips and microfluidic reactor systems. Our patented technology allows massively parallel synthesis of DNA oligomers and peptides on silicon/glass and plastic chips. In terms of application we are focusing on diagnostic applications in the area of water and food safety as well as medical diagnostics. For the future our focus will be slightly shifting towards massively parallel PCR based detection assays and to making combinatorial libraries of Si RNAs as well as synthetic genes. We collaborate extensively with colleagues in U of M and MSU.
Increased motor vehicle and electrical power usage demands continual improvement of air cleaning and hydrogen purification catalysts. We are developing and testing new supported catalysts by incorporating pre- synthesized metal crystallites in oxide supports by single step sol-gel processing. This method enables us to independently vary the metal crystallite size and the loading. So far this method has enabled us to make superior silver, gold, copper, and platinum based catalysts. However many challenges still remain in increasing the activity of the catalysts by a factor of almost ten and making them robust against poisoning and sintering. We have an ongoing collaboration in this area with colleagues from Ford Motor Co.
K. Lee, J. M. Rouillard 2, B. Kim, E. Gulari, and J. Kim, “ConjugatedPolymers Combined with a Molecular Beacon for Label-Free andSelf-Signal-Amplifying DNA Microarrays,” Advanced Functional Materials,19, 20, 3317 – 3325 Published Online: 2009.
O. Srivannavit, M. Gulari, Z. Hua, X. Gao, X. Zhou, A. Hong, T.Zhou, and E. Gulari, “Microfluidic reactor array device for massivelyparallel in situ synthesis of oligonucleotide,” Sensors and ActuatorsB: Chemical, 140, 2, 16, 473-481, 2009.
J. M. Rouillard and E. Gulari, “OligoArrayDb: pangenomic oligonucleotidemicroarray probe sets database,” Nucleic Acids Research,1–4,doi:10.1093/nar/gkn761, 2008.
R. D. Stedtfeld, S. W. Baushke, D. M. Tourlousse, S. M. Miller, T. M.Stedtfeld, E. Gulari, J. M. Tiedje, and S. A. Hashsham, “Developmentand Experimental Validation of a Predictive Threshold Cycle Equationfor Quantification of Virulence and Marker Genes by High-ThroughputNanoliter-Volume PCR on the OpenArray Platform,” Applied andEnvironmental Microbiology, 74, 12, 3831-3838, 2008.
W. Thitsartarn, E. Gulari , S. Wongkasemjit, “Synthesis of Fe-MCM-41from silatrane and FeCl3 via sol-gel process and its epoxidationactivity,” Applied Organometallic Chemistry, 22, 2, 97 – 103, PublishedOnline: 2008.
S. Chavadeja, P. Phuaphromyoda, E. Gulari, P. Rangsunvigita and T.Sreethawong, “Photocatalytic degradation of 2-propanol by using Pt/TiO2prepared by microemulsion technique,” Chemical Engineering Journal,137, 3, 489, 2008.
K. Lee, K. Maisel, J.M. Rouillard, E. Gulari, and J. Kim*,"Sensitive andSelective Label-Free DNA Detection by Conjugated Polymer-BasedMicroarrays and Intercalating Dye," Chem. Mater., 20, 2848 – 2850, 2008.
S.M. Miller, D.M. Tourlousse, R.D. Stedtfeld, S.W. Baushke, A.B.Herzog, L.M. Wick, J.M. Rouillard, E. Gulari, J.M. Tiedje, and S.A.Hashsham, “In situ-synthesized virulence and marker gene biochip fordetection of bacterial pathogens in water,” Applied and EnvironmentalMicrobiology, 74, 70099-2240/08/$08.00+0, 2200-2209,doi:10.1128/AEM.01962-07, 2008.
Z. Hua, R. Pal, M. Burns and E. Gulari, “A Light Writable Microfluidic "Flash Memory": optically addressed actuator array with latched operation for microfluidic applications,”, Lab. Chip., 8, 488-491, 2008.
Courses Taught at the University of Michigan
Undergraduate ChE Courses
ChE 460 - Chemical Engineering Laboratory II
Graduate ChE Courses
ChE 507 - Mathematical Modeling in Chemical Engineering
ChE 542 - Intermediate Transport Phenomena