Skip to Main Content
  • Home
  • About
    • About CHE
    • History
      • Department History
      • Department Chairs
      • Faculty Textbooks
    • Facts and Figures
    • Department Publications
    • Visit Us
    • Contact Us
  • Calendar
  • News
    • Chemical Engineering News
    • In the News
  • Research
    • Department Research
    • Research Areas
      • CHE Research Areas
      • Catalysis and Reactions
      • Biomolecular Engineering
      • Cellular Engineering
      • Sustainable Energy
      • Computing and Simulation
      • Nanotechnology
      • Materials
      • Microfabricated Systems
      • Polymers and Complex Fluids
    • Research Programs for Undergraduates
      • Undergraduate Research Opportunities
      • Work in Faculty Labs
    • Partners in Industry
  • People
    • Faculty
      • All Faculty
      • Core Faculty
      • Affiliated Faculty
      • Research Faculty
      • Adjunct Faculty
      • Emeritus Faculty
    • Staff
    • Student Support
    • Faculty and Staff Directory
    • Postdoctoral Research Fellows
    • Graduate Students
  • Graduate
    • Graduate
    • Program
      • Graduate Program
      • Graduate Degree Requirements
      • SUGS
      • Additional Options
      • Doctoral Candidacy Exam
      • Thesis Proposal Exam
      • Doctoral Committee
    • Prospective Students
      • Applying to Graduate Program
      • Admissions Requirements
      • Admissions Timeline
      • TOEFL & GRE
      • Financial Support
    • Current Graduate Students
      • Current Students
      • GSI Positions
    • Graduate Contacts
    • Why Michigan?
  • Undergraduate
    • Undergraduate
    • Program
      • Undergraduate Program
      • Mission
      • Incorporating Outreach
      • Program Improvement
      • Enrollment Data
    • Join Chemical Engineering
    • Degree Requirements
      • Undergraduate Degree Requirements
      • Intellectual Breadth
      • Courses & Course Profiles
    • Minors, Concentrations and Specialized Studies
    • Dual and Combined Degrees
    • Masters and SUGS Programs
    • Jobs and Research
      • Jobs and Research
      • Cooperative Education
    • Student Resources
      • Student Resources
      • Scholarships
      • FAQ
    • Student Groups
      • Student Organizations
      • Funding for Group
    • Undergraduate Contacts
  • Careers
    • Career Information
    • What is a Chemical Engineer?
    • Career Pathways
    • Employers of Chemical Engineers
    • Professional Engineer License
    • Recruit Talent
  • Alumni
    • CHE Alumni
    • Stay Informed
      • Stay Informed
      • Alumni Updates
      • Alumni Profiles
    • Reconnect
      • Reconnect
      • Flat Charlie
    • Giving
Chemical Engineering
Chemical Engineering
CONNECT WITH US:
About
Research
People
Graduate
Undergraduate
Alumni
  • About
    • History
    • Facts and Figures
    • Department Publications
    • ChE Faculty Search
    • CHE Seminar Series
    • Annual Department Events
    • Visit Us
    • Contact Us
  • Calendar
    • CHE Seminar Series
  • Research
    • Research Areas
    • Facilities
    • Research Programs for Undergraduates
    • Partners in Industry
  • News
    • In the News
  • People
    • Faculty
    • Staff
    • Student Support
    • Faculty and Staff Directory
    • Postdoctoral Research Fellows
    • Graduate Students
  • Graduate
    • Program
    • Prospective Students
    • Current Students
    • Graduate Contacts
    • Why Michigan?
    • Housing
  • Undergraduate
    • Program
    • Join Chemical Engineering
    • Degree Requirements
    • Minors and Concentrations
    • Dual and Combined Degrees
    • Masters and SUGS Programs
    • Jobs and Research
    • Student Resources
    • Student Groups
    • Undergraduate Contacts
  • Alumni
    • Stay Informed
    • Reconnect
    • Giving
  • Careers
    • What is a Chemical Engineer?
    • Career Pathways
    • Employers of Chemical Engineers
    • Professional Engineer License
    • Recruit Talent
HOME/People/Faculty/Core Faculty/Lola Eniola-Adefeso

Lola Eniola-Adefeso

Lola Eniola-Adefeso

University Diversity and Social Transformation Professor of Chemical Engineering

Professor

Miller Faculty Scholar

Vice Chair for Graduate Education


Chemical Engineering

B-28 G072W NCRC

2800 Plymouth Road, Ann Arbor, MI 48109-2800

lolaa@umich.edu

(734) 936-0856

website

Related Links
Education Research Interests Biography Awards Publications

Education:

University of Pennsylvania
PhD Chemical and Biomolecular Engineering ’04
MSE Chemical and Biomolecular Engineering ’00

University of Maryland, Baltimore County
BSE Chemical and Biomolecular Engineering ’99

 

Research Interests: ^top

Due to their high specific interaction with their counter-receptors and their carefully regulated expression (limit to inflammation), leukocyte-endothelium adhesion molecules (LECAM) are attractive molecules for vascular targeting in human diseases in which inflammation plays a role. Our research goal is to use knowledge of the cellular inflammatory response and blood flow dynamics to design bio-functionalized particles for targeted drug delivery and imaging.

Work in the lab is divided into 3 major groups:

  1. Cell Adhesion and Migration – Cells of the immune system.
    Our goal is to use in vitro experimental setups to understand the receptor-ligand interactions involved in leukocyte firm arrest and transmigration.
  2. Design of polymeric cells for targeted drug delivery.
    We are working on designing sophisticated leukocyte mimetics that can target therapeutics to diseased vasculature via multiple receptor-ligand interactions with applications in cardiovascular disease and cancer.
  3. Smart Biomaterials for Drug Delivery.
    We working closely with polymer chemists and material scientist to identify new materials for drug delivery. Our work in this area is currently focused on immune response to new materials.

Biography: ^top

Professional Experience

University of Michigan
Chemical Engineering Department
Ann Arbor, Michigan
Professor, 2017-present
Associate Professor, 2014-2017
Assistant Professor, 2006-2014

Baylor College of Medicine
Pediatrics/Leukocyte Biology
Houston, Texas, 2004-2006

Courses Taught

Undergraduate ChE Courses
ChE 230 – Material and Energy Balance, Fall 2009, Fall 2010
ChE 342 – Mass and Heat Transfer, Fall 2006, Fall 2007, Fall 2008
Student Projects

Graduate ChE Courses
ChE 696 – Engineering Principle in Drug Delivery and Targeting, Winter 2010

 

Awards: ^top

Senior Fellow, Michigan Society of Fellows, 2017

American Institute for Medical and Biological Engineering, Fellow, 2017

American Institute of Chemical Engineers, Women’s Initiatives Committee’s Mentorship Excellence Award, 2017

American Institute of Chemical Engineers, Minority Affairs Committee’s William W. Grimes Award for Excellence in Chemical Engineering, 2017

Raymond J. and Monica E. Schultz Outreach and Diversity Award, 2017
College of Engineering, University of Michigan

Harold R. Johnson Diversity Service Award (2016)
The University of Michigan

NAE Frontier of Engineering Education, Selected Participant (2012)

Provost Teaching Innovation Award (2012)
The University of Michigan

Departmental Research Achievement Award (2012)
Department of Chemical Engineering at the University of Michigan

NSF CAREER (2011)
National Science Foundation

Innovator Award (2010)
American Heart Association

Scientist Development Grant (2007)
American Heart Association

University of Michigan Rackham Faculty Development Grant, 2006
APS/NIDDK Travel Fellowship Awards: EB, 2006

Baylor College of Medicine NIH T32 Training Grant in Lung Disease, 2004 – 2006

Janice Lumpkin Awards For Excellence in Arts & Sciences, 2003

NASA Graduate Research Fellowship, 2002-2004

GEM Masters Fellowship in Engineering, 1999

UMBC Meyerhoff Scholarship, 1997-1999

UMBC MARC U* STAR Scholar, 1998 – 1999

Publications: ^top

  • Heslinga, M.J., G.M. Willis, D. Sobzynski, A.J. Thompson and O. Eniola-Adefeso. (2013) “One-Step Fabrication of Agent-Loaded Biodegradable Microspheroids for Drug Delivery and Imaging Applications.” Submitted.
  • Onyskiw, P. and O. Eniola-Adefeso. (2013) “Effect of PEGylation on Ligand-Based Targeting of Drug Carriers to the Vascular Wall in Blood Flow.” Langmuir. 2013. 29(35):11127-34.
  • Thompson, A.J., E.M. Mastria, O. Eniola-Adefeso (2013) “The Margination Propensity of Ellipsoidal Micro/Nanoparticles to the Endothelium in Human Blood Flow” Biomaterials. 2013. 34(23):5863-71.
  • Huang, R.B., A.L. Gonzalez, and O. Eniola-Adefeso. (2013) “Laminar Shear Stress Elicit Distinct Endothelial Cell E-Selectin Expression Pattern via TNFα and IL-1β Activation.” Biotechnology & Bioengineering. 2013. 110(3): 999-1003.
  • Namdee, K., A.J. Thompson, P. Charoenphol and O. Eniola-Adefeso. (2013) “Margination propensity of vascular-targeted spheres from blood flow in a microfluidic model of human microvessels.” Langmuir. 2013. 29(8): 2530-2535.
  • Charoenphol, P., P. Onyskiw and O. Eniola-Adefeso. (2012) “Particle-Cell Dynamics in Human Blood Flow: Implications for Vascular-Targeted Drug Delivery.” Journal of Biomechanics. 2012. 45(16):2822-2828.
  • Heslinga, M.J., T.M. Porter and O. Eniola-Adefeso. Design of nanovectors for therapy and imaging of cardiovascular diseases. Methodists: Debakey Cardiovascular Journal, 2012. 8(1): 13-17.
  • Huang, R.B. and O. Eniola-Adefeso. “Shear stress modulation of IL-1β-induced E-selectin expression in human endothelial cells.” PLoS One, 2012. 7(2): e31874.
    Charoenphol, P., S. Mocherla, D. Dubois, K. Namdee and O. Eniola-Adefeso. “Targeting therapeutics to the vascular wall in atherosclerosis – Carrier size matters.” Atherosclerosis, 2011. 217(2): 364-70.
  • Huang, R.B., S. Mocherla, M.J. Heslinga, P. Charoenphol, and O. Eniola-Adefeso. “Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery.” Molecular Membrane Biology, 2010. 27(4-6): 190-205. Second most read article summer 2010.
  • Eniola-Adefeso, O. Bringing Outreach Into the Engineering Classroom – A Mass and Heat Transfer Course Project. Chemical Engineering Education, 2010. 44(4): 280.
  • Charoenphol, P., R.B. Huang and O. Eniola-Adefeso. “Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers.” Biomaterials, 2010. 31(6): 1392-402.
  • Heslinga, M.J., E.M. Mastria* and O. Eniola-Adefeso. Fabrication of biodegradable spheroidal microparticles for drug delivery applications. Journal of Controlled Release, 2009. 138(3): 235-242.
  • Eniola-Adefeso, O., R.B. Huang and C.W. Smith. Kinetics of LFA-1 Mediated Adhesion of Human Neutrophils to ICAM-1 – Role of E-Selectin Signaling Post-Activation. Annals of Biomedical Engineering, 2009. 37(4): 737-48.
  • Eniola, A.O. and D.A. Hammer. In vitro characterization of leukocyte mimetic for targeting therapeutics to the endothelium using two receptors. Biomaterials, 2005. 26(34): 7136-44.
  • Eniola, A.O., E.F. Krasik, L.A. Smith, S. Gang, and D.A. Hammer. I-domain of lymphocyte function-associated antigen-1 mediates rolling of polystyrene particles on ICAM-1 under flow. Biophysical Journal, 2005. 89: 3577-88.
  • Eniola, A.O. and D.A. Hammer. Characterization of biodegradable drug delivery vehicles with the adhesive properties of leukocytes II: Effect of degradation on targeting efficiency. Biomaterials, 2005. 26(6): 661-670.
  • Eniola, A.O., P.J. Willcox and D.A. Hammer. Quantifying Interplay between rolling and firm adhesion elucidated with a cell-free system engineered with two distinct receptor-ligand pairs. Biophysical Journal, 2003. 85(4): 2720-31.
  • Zhang, Y., A.O. Eniola, D.J. Graves, and D.A. Hammer. Specific Adhesion of Micron-Sized Colloids to Surfaces Mediated by DNA Hybridization. Langmuir, 2003. 19(17): 6905-11.
  • Eniola, A.O. and D.A. Hammer. Artificial polymeric cells for targeted drug delivery. Journal of Controlled Release, 2003. 87(1-3): 18-22.
  • Eniola, A.O., S.D. Rodgers and D.A. Hammer. Characterization of biodegradable drug delivery vehicles with the adhesive properties of leukocytes. Biomaterials, 2002. 23(10): 2167-77.
  • Eniola, A.O. and J.A. Lumpkin. Reducing metal-catalyzed oxidation during immobilized Cu-Iminodiacetic acid metal affinity chromatography. Proceedings National Conference of Undergraduate Research, 1998. Volume III: 989-91.
People
  • People
    • Faculty
      • Core Faculty
      • Affiliated Faculty
      • Lecturers
      • Research Faculty
      • Adjunct Faculty
      • Emeritus Faculty
      • All Faculty
  • Staff
  • Student Support
  • Faculty and Staff Directory
  • Postdoctoral Research Fellows
  • Graduate Students
Research Area
  • Biomolecular Engineering
  • Catalysis & Reactions
  • Cellular Engineering
  • Computing & Simulation
  • Energy
  • Materials
  • Microfabricated Systems
  • Nanotechnology
  • Polymers & Complex Fluids
College of Engineering | University of Michigan
Chemical Engineering

3074 H.H. Dow

2300 Hayward Street

Ann Arbor, MI 48109-2136

Phone: (734) 764-2383

Fax: (734) 763-0459

cheme@umich.edu

Give to Chemical Engineering »

Follow The College

Facebook

Twitter

Instagram

LinkedIn

YouTube

ALWAYS INNOVATING. FOREVER VALIANT.

The Michigan Engineering Bicentennial Web Project is a multimedia story collection.

See all stories »

  • © The Regents of the University of Michigan Ann Arbor, MI 48109 USA
  • Privacy Policy
  • Non-Discrimination Policy
  • Campus Safety
  • U-M Gateway
  • Give Feedback